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Literature summary for 3.4.16.4 extracted from
- Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution (2001), J. Biol. Chem., 276, 616-623.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| three dimensional structure of the G105D mutant enzyme at 2.3 A resolution | Escherichia coli |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| G105D | mutation markedly impairs the beta-lactamase activity, with only minor effects on acylation, and promotes accumulation of a covalent complex with peptide substrates | Escherichia coli |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme forms a covalent acyl-enzyme complex with beta-lactam antibiotics | Escherichia coli | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| penicillin-binding protein 5 | - |
Escherichia coli |
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