Any feedback?
Literature summary for 3.4.15.1 extracted from
- Characterization of chicken lung angiotensin I-converting enzyme (1992), J. Endocrinol., 132, 261-268.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Cl- | activates | Gallus gallus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| angiotensin II | - |
Gallus gallus | |
| captopril | - |
Gallus gallus | |
| EDTA | - |
Gallus gallus | |
| His-Leu | - |
Gallus gallus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.065 | - |
angiotensin I | detergent-solubilized enzyme | Gallus gallus | |
| 0.078 | - |
angiotensin I | trypsin-extracted enzyme | Gallus gallus | |
| 0.32 | - |
hippuryl-His-Leu | detergent-solubilized enzyme | Gallus gallus | |
| 0.52 | - |
hippuryl-His-Leu | trypsin-extracted enzyme | Gallus gallus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Gallus gallus | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zinc | contains approximately 1 gatom of zinc per mol of enzyme | Gallus gallus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | glycoprotein | Gallus gallus |
| side-chain modification | hexoses are the most abundant residues | Gallus gallus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Gallus gallus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| angiotensin I + H2O | - |
Gallus gallus | angiotensin II + His-Leu | - |
? | |
| bradykinin + H2O | - |
Gallus gallus | Phe-Arg + Ser-Pro + Arg-Pro-Pro-Gly-Phe | - |
? | |
| hippuryl-His-Leu + H2O | - |
Gallus gallus | hippuric acid + His-Leu | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2.95 | - |
angiotensin I | detergent-solubilized enzyme | Gallus gallus | |
| 5.4 | - |
hippuryl-His-Leu | detergent-solubilized enzyme | Gallus gallus | |
| 6.58 | - |
angiotensin I | trypsin-extracted enzyme | Gallus gallus | |
| 8.58 | - |
hippuryl-His-Leu | trypsin-extracted enzyme | Gallus gallus | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.3 | 8.7 | - |
Gallus gallus |
| 8.5 | - |
hydrolysis of hippuryl-His-Leu | Gallus gallus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
