Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Homo sapiens | |
2,3-dimercapto-1-propanol | - |
Homo sapiens | |
2-mercaptoethanol | - |
Homo sapiens | |
8-hydroxyquinoline | - |
Homo sapiens | |
bradykinin potentiator C | - |
Homo sapiens | |
captopril | - |
Homo sapiens | |
dithiothreitol | - |
Homo sapiens | |
EDTA | - |
Homo sapiens | |
guanethidine | weak | Homo sapiens | |
SDS | weak | Homo sapiens | |
Teprotide | - |
Homo sapiens | |
Urea | weak | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2 | - |
hippuryl-His-Leu | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
170000 | - |
x * 170000, kidney, SDS-PAGE of the reduced enzyme | Homo sapiens |
199000 | - |
equilibrium sedimentation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | glycoprotein | Homo sapiens |
side-chain modification | 13% neutral sugar | Homo sapiens |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | cortex | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hippuryl-His-Leu + H2O | - |
Homo sapiens | hippuric acid + His-Leu | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 170000, kidney, SDS-PAGE of the reduced enzyme | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
5-30 min, stable | Homo sapiens |
50 | - |
10 min, 60% loss of activity | Homo sapiens |
55 | - |
10 min, 80% loss of activity | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
545 | - |
hippuryl-His-Leu | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.2 | 8.4 | hydrolysis of hippuryl-His-Leu | Homo sapiens |