Application | Comment | Organism |
---|---|---|
medicine | evaluation of effects of angiotensin-converting enzyme inhibitors and pharmacogenetic interaction on the survival of the patients with diastolic heart failure, overview | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | influence of ACE gene insertion/deletion polymorphisms, rs1799752, D-and I-alleles, on ACE inhibitor effects in treatment of heart failure, comparison to effects of polymorphisms of angiotensionogen gene, i.e. T174M, M235T, G6A, A20C, G152A, and G217A, and of the A1166C polymorphisms of the angiotensin II type I receptor, overview. The genetic variants in the renin-angiotensin system genes are associated with long-term mortality and cardiovascular events in the patients with diastolic heart failure, but can be modified by the use of ACE inhibitors | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | use of ACE inhibitor is associated with a significant decrease in long-term mortality and cardiovascular events in the patients with diastolic heart failure | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ACE | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | use of ACE inhibitor is associated with a significant decrease in long-term mortality and cardiovascular events in the patients with diastolic heart failure | Homo sapiens |