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Literature summary for 3.4.15.1 extracted from
- Characterization of dipeptidylcarboxypeptidase of Leishmania donovani: a molecular model for structure based design of antileishmanials (2010), J. Comput. Aided Mol. Des., 24, 77-87.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli strain BL21(DE3) | Leishmania donovani |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| bradykinin potentiating peptide | i.e. BPP1 or pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro | Leishmania donovani | |
| captopril | binding mode, molecular docking, detailed overview | Leishmania donovani |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 4 | - |
hippuryl-His-Leu | - |
Leishmania donovani | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania donovani | Q4KXL2 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant enzyme from Escherichia coli strain BL21(DE3) to homogeneity | Leishmania donovani |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hippuryl-His-Leu + H2O | - |
Leishmania donovani | hippuric acid + His-Leu | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | enzyme homology modelling, overview | Leishmania donovani |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACE | - |
Leishmania donovani |
| DCP | - |
Leishmania donovani |
| dipeptidylcarboxypeptidase | - |
Leishmania donovani |
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