Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibition of angiotensin-converting enzyme, or angiotensin II receptor blockage, slows down the progression of renal disease and provide a renal-protective effect. Therefore, they are used in therapy of type 2 diabetes, the main cause of end-stage renal disease in Europe and the United States, antagonizing the diabetic nephropathy progresses, overview | Homo sapiens | |
ramipril | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | Homo sapiens | - |
angiotensin II + His-Leu | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | - |
Homo sapiens | angiotensin II + His-Leu | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACE | - |
Homo sapiens |
angiotensin-converting enzyme | - |
Homo sapiens |