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Literature summary for 3.4.15.1 extracted from
- Cost-effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in newly diagnosed type 2 diabetes in Germany (2010), Int. J. Technol. Assess. Health Care, 26, 62-70.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | inhibition of angiotensin-converting enzyme, or angiotensin II receptor blockage, slows down the progression of renal disease and provide a renal-protective effect. Therefore, they are used in therapy of type 2 diabetes, the main cause of end-stage renal disease in Europe and the United States, antagonizing the diabetic nephropathy progresses, overview | Homo sapiens | |
| ramipril | - |
Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| angiotensin I + H2O | Homo sapiens | - |
angiotensin II + His-Leu | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| angiotensin I + H2O | - |
Homo sapiens | angiotensin II + His-Leu | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACE | - |
Homo sapiens |
| angiotensin-converting enzyme | - |
Homo sapiens |
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