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Literature summary for 3.4.15.1 extracted from

  • Lee, J.K.; Hong, S.; Jeon, J.K.; Kim, S.K.; Byun, H.G.
    Purification and characterization of angiotensin I converting enzyme inhibitory peptides from the rotifer, Brachionus rotundiformis (2009), Biores. Technol., 100, 5255-5259.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Asp-Asp-Thr-Gly-His-Asp-Phe-Glu-Asp-Thr-Gly-Glu-Ala-Met an inhibitory peptide from the marine rotifer, Brachionus rotundiformis Oryctolagus cuniculus
additional information ACE inhibitory peptides from the marine rotifer, Brachionus rotundiformis, overview. The hydrolysate is prepared by Alcalase, a-chymotrypsin, Neutrase, papain, and trypsin, inhibitory activities of the different preparateions, overview. Glutamic acid, aspartic acid, proline, glycine and alanine from ACE inhibitory activity peptide are all observed in many other ACE inhibitory peptides. Peptides derived from rotifers may be beneficial as anti-hypertension compounds in functional foods resource Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
Oryctolagus cuniculus
-
lung acetone powder Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hippuryl-His-Leu + H2O
-
Oryctolagus cuniculus hippuric acid + His-Leu
-
?

Synonyms

Synonyms Comment Organism
ACE
-
Oryctolagus cuniculus
angiotensin I converting enzyme
-
Oryctolagus cuniculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Oryctolagus cuniculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
IC50 value of alcalase hydrolysate of Brachionus rotundiformis inhibitory peptides for ACE inhibitory activity is 0.63 mg/ml Oryctolagus cuniculus additional information
0.00964
-
-
Oryctolagus cuniculus Asp-Asp-Thr-Gly-His-Asp-Phe-Glu-Asp-Thr-Gly-Glu-Ala-Met