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Literature summary for 3.4.15.1 extracted from

  • Pentzien, A.K.; Meisel, H.
    Transepithelial transport and stability in blood serum of angiotensin-I-converting enzyme inhibitory dipeptides (2008), Z. Naturforsch. C, 63, 451-459.
    View publication on PubMed
Search for more literature for 3.4.15.1

Inhibitors

Inhibitors Comment Organism Structure
L-Ala-L-Trp
-
 Homo sapiens
L-Ala-L-Trp
-
 Oryctolagus cuniculus
L-Val-L-Phe
-
 Homo sapiens
L-Val-L-Phe
-
 Oryctolagus cuniculus
L-Val-L-Tyr
-
 Homo sapiens
L-Val-L-Tyr
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensin I + H2O Homo sapiens
-
 angiotensin II + L-His-L-Leu
-
 ?
angiotensin I + H2O Oryctolagus cuniculus
-
 angiotensin II + L-His-L-Leu
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Oryctolagus cuniculus
-
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
 Homo sapiens angiotensin II + L-His-L-Leu
-
 ?
angiotensin I + H2O
-
 Oryctolagus cuniculus angiotensin II + L-His-L-Leu
-
 ?
hippuryl-L-His-L-Leu + H2O
-
 Homo sapiens hippuric acid + L-His-L-Leu
-
 ?
hippuryl-L-His-L-Leu + H2O
-
 Oryctolagus cuniculus hippuric acid + L-His-L-Leu
-
 ?

Synonyms

Synonyms Comment Organism
ACE
-
 Homo sapiens
ACE
-
 Oryctolagus cuniculus
angiotensin-I-converting enzyme
-
 Homo sapiens
angiotensin-I-converting enzyme
-
 Oryctolagus cuniculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0065
-
 in 0.1 mM sodium borate buffer, 0.3 mM NaCl, pH 8.3, at 37°C Oryctolagus cuniculus L-Ala-L-Trp
0.0122
-
 in 0.1 mM sodium borate buffer, 0.3 mM NaCl, pH 8.3, at 37°C Oryctolagus cuniculus L-Val-L-Tyr
0.051
-
 in 0.1 mM sodium borate buffer, 0.3 mM NaCl, pH 8.3, at 37°C Oryctolagus cuniculus L-Val-L-Phe