Cloned (Comment) | Organism |
---|---|
expression in CHO-K1 cells | Xanthomonas axonopodis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
captopril | - |
Xanthomonas axonopodis | |
delaprilat | weak | Xanthomonas axonopodis | |
EDTA | - |
Xanthomonas axonopodis | |
enalaprilat | - |
Xanthomonas axonopodis | |
fosinoprilat | - |
Xanthomonas axonopodis | |
lisinopril | weak | Xanthomonas axonopodis | |
perindoprilat | weak | Xanthomonas axonopodis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
periplasmic space | XcACE is constituvely expressed and is likely to be secreted and further localised in the periplasmic space | Xanthomonas axonopodis | 42597 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | XcACE activity depends on zinc binding. Hydrolysis of 7-methoxycoumarin-4-yl-diacetyl-SDKP-N3 (2,4-dinitrophenyl)L-2,3-diaminopropionyl-OH is abolished after zinc chelation with EDTA and dialysis but is restored by zinc addition | Xanthomonas axonopodis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Xanthomonas axonopodis | - |
pv. citri | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | - |
Xanthomonas axonopodis | angiotensin II + His-Leu | - |
? | |
hippuryl-His-Leu + H2O | - |
Xanthomonas axonopodis | hippuric acid + His-Leu | - |
? |
Synonyms | Comment | Organism |
---|---|---|
XcACE | - |
Xanthomonas axonopodis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00003 | - |
- |
Xanthomonas axonopodis | fosinoprilat | |
0.00016 | - |
- |
Xanthomonas axonopodis | captopril |