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Literature summary for 3.4.15.1 extracted from

  • Actis-Goretta, L.; Ottaviani, J.I.; Fraga, C.G.
    Inhibition of angiotensin converting enzyme activity by flavanol-rich foods (2006), J. Agric. Food Chem., 54, 229-234.
    View publication on PubMed
Search for more literature for 3.4.15.1

Inhibitors

Inhibitors Comment Organism Structure
(+)-catechin IC50: about 1.6 mM Oryctolagus cuniculus
(-)-epicatechin IC50: about 1.7 mM Oryctolagus cuniculus
caffeic acid IC50: about 1.7 mM Oryctolagus cuniculus
chlorogenic acid IC50: about 1.8 mM Oryctolagus cuniculus
epigallocatechin IC50: about 0.3 mM Oryctolagus cuniculus
flavanol flavanols either isolated or present in foods can inhibit enzyme activity Oryctolagus cuniculus
gallic acid IC50 : about 1.7 mM Oryctolagus cuniculus
kaempferol IC50: about 1.2 mM Oryctolagus cuniculus
quercetin IC50: about 2.0 mM Oryctolagus cuniculus
resveratrol IC50: about 1.6 mM Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hippuryl-His-Leu + H2O
-
 Oryctolagus cuniculus hippuric acid + His-Leu
-
 ?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.3
-
 IC50: about 0.3 mM Oryctolagus cuniculus epigallocatechin
1.2
-
 IC50: about 1.2 mM Oryctolagus cuniculus kaempferol
1.6
-
 IC50: about 1.6 mM Oryctolagus cuniculus resveratrol
1.6
-
 IC50: about 1.6 mM Oryctolagus cuniculus (+)-catechin
1.7
-
 IC50 : about 1.7 mM Oryctolagus cuniculus gallic acid
1.7
-
 IC50: about 1.7 mM Oryctolagus cuniculus caffeic acid
1.7
-
 IC50: about 1.7 mM Oryctolagus cuniculus (-)-epicatechin
1.8
-
 IC50: about 1.8 mM Oryctolagus cuniculus chlorogenic acid
2
-
 IC50: about 2.0 mM Oryctolagus cuniculus quercetin