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Literature summary for 3.4.15.1 extracted from

  • Brunner, D.B.; Desponds, G.; Biollaz, J.; Keller, I.; Ferber, F.; Gavras, H.; Brunner, H.R.; Schelling, J.L.
    Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects. (discussion S785-777) 1981 (2004), Br. J. Clin. Pharmacol., 58, S778-784.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
N-[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline i.e. MK 421. Effect of the inhibitor on the components of the renin system in healthy subjects : the drug has a prolonged duration of action and effectively reduces plasma converting enzyme activity, angiotensin II and aldosterone levels and thereby increases sodium diuresis Homo sapiens
N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline effect of the inhibitor on the components of the renin system in healthy subjects : the drug has a prolonged duration of action and effectively reduces plasma converting enzyme activity, angiotensin II and aldosterone levels and thereby increases sodium diuresis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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