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Literature summary for 3.4.15.1 extracted from

  • Cotton, J.; Hayashi, M.A.F.; Cuniasse, P.; Vazeux, G.; Ianzer, D.; De Camargo, A.C.M.; Dive, V.
    Selective inhibition of the C-domain of angiotensin I converting enzyme by bradykinin potentiating peptides (2002), Biochemistry, 41, 6065-6071.
    View publication on PubMed
Search for more literature for 3.4.15.1

Inhibitors

Inhibitors Comment Organism Structure
pGlu-Asn-Trp-Pro-His-Pro-Gln-Ile-Pro-Pro
-
 Homo sapiens
pGlu-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro
-
 Homo sapiens
pGlu-Gly-Leu-Pro-Pro-Gly-Pro-Pro-Ile-Pro-Pro
-
 Homo sapiens
pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro
-
 Homo sapiens
RXP407
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl) + H2O
-
 Homo sapiens ?
-
 ?
(7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl) + H2O
-
 Homo sapiens ?
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000001
-
 pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.000001
-
 pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.0000015
-
 pGlu-Asn-Trp-Pro-His-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.0000015
-
 pGlu-Asn-Trp-Pro-His-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.000007
-
 RXP407 pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.000007
-
 RXP407 pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.00003
-
 pGlu-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.00003
-
 pGlu-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.00008
-
 pGlu-Gly-Leu-Pro-Pro-Gly-Pro-Pro-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.00008
-
 pGlu-Gly-Leu-Pro-Pro-Gly-Pro-Pro-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.00008
-
 pGlu-Gly-Leu-Pro-Pro-Gly-Pro-Pro-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.00008
-
 pGlu-Gly-Leu-Pro-Pro-Gly-Pro-Pro-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.0001
-
 pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.0001
-
 pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.0002
-
 pGlu-Asn-Trp-Pro-His-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.0002
-
 pGlu-Asn-Trp-Pro-His-Pro-Gln-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.001
-
 RXP407 pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.004
-
 RXP407 pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), C-domain Homo sapiens
0.008
-
 pGlu-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens
0.01
-
 pGlu-Gly-Leu-Pro-Pro-Arg-Pro-Lys-Ile-Pro-Pro pH 6.8, 25°C, reaction with (7-methoxycoumarin-2-acetic acid)-Ala-Ser-Asp-Lys-(N3-(2,4-dinitrophenyl)-L-2,3-diaminopropyl), N-domain Homo sapiens