Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
B-type natriuretic peptide (1-32) + H2O | DPP IV removes the two amino terminal amino acids (Ser-Pro) from B-type natriuretic peptide (1-32) to produce B-type natriuretic peptide (3-32) | Homo sapiens | B-type natriuretic peptide (3-32) + L-Ser-L-Pro | - |
? | |
B-type natriuretic propeptide (1-108) + H2O | - |
Homo sapiens | B-type natriuretic propeptide (3-306) + ? | - |
? | |
additional information | the substrate specificity of DPP IV is not that strict and cleavage after the penultimate Ser, Gly, Thr, Val, and Leu has also been observed | Homo sapiens | ? | - |
? | |
N-terminal B-type natriuretic propeptide (1-76) + H2O | - |
Homo sapiens | N-terminal B-type natriuretic propeptide (3-76) + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
adenosine deaminase-binding protein | - |
Homo sapiens |
CD26 | - |
Homo sapiens |
DPP IV | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | DPP IV activity isincreased in plasma of hypertensive patients with concomitant pulmonary hypertension and in atrial tissue of patients with chronic persistent atrial fibrillation | up |