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Literature summary for 3.4.14.5 extracted from

  • Matsuyama-Yokono, A.; Tahara, A.; Nakano, R.; Someya, Y.; Hayakawa, M.; Shibasaki, M.
    Chronic inhibition of dipeptidyl peptidase-IV with ASP8497 improved the HbA(1c) level, glucose intolerance, and lipid parameter level in streptozotocin-nicotinamide-induced diabetic mice (2009), Naunyn Schmiedebergs Arch. Pharmacol., 379, 191-199.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
ASP8497 i.e. (2S,4S)-4-fluoro-1-([[4-methyl-1-(methylsulfonyl)piperidin-4-yl]amino]acetyl)pyrrolidine-2-carbonitrile monofumarate, potent DPP-IV inhibitor and potential agent for the treatment of type 2 diabetes Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucagon-like peptide 1 + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glucagon-like peptide 1 + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
dipeptidyl peptidase-IV
-
 Mus musculus
DPP-IV
-
 Mus musculus