Literature summary for 3.4.14.5 extracted from

Fuchs, H.; Tillement, J.P.; Urien, S.; Greischel, A.; Roth, W.
Concentration-dependent plasma protein binding of the novel dipeptidyl peptidase 4 inhibitor BI 1356 due to saturable binding to its target in plasma of mice, rats and humans (2009), J. Pharm. Pharmacol., 61, 55-62.

Search for more literature for 3.4.14.5

Inhibitors

Inhibitors	Comment	Organism	Structure
BI 1356	proposed trade name ONDERO, exhibits a prominent concentration-dependent plasma protein binding due to a saturable high affinity binding to the DPP-4 target in plasma	Homo sapiens
BI 1356	proposed trade name ONDERO, exhibits a prominent concentration-dependent plasma protein binding due to a saturable high affinity binding to the DPP-4 target in plasma	Mus musculus
BI 1356	proposed trade name ONDERO, exhibits a prominent concentration-dependent plasma protein binding due to a saturable high affinity binding to the DPP-4 target in plasma	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
glucagon-like peptide 1 + H2O	Mus musculus	-	?	-	?
glucagon-like peptide 1 + H2O	Homo sapiens	-	?	-	?
glucagon-like peptide 1 + H2O	Rattus norvegicus	-	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
glucagon-like peptide 1 + H2O	-	Mus musculus	?	-	?
glucagon-like peptide 1 + H2O	-	Homo sapiens	?	-	?
glucagon-like peptide 1 + H2O	-	Rattus norvegicus	?	-	?

Synonyms

Synonyms	Comment	Organism
dipeptidyl peptidase 4	-	Mus musculus
dipeptidyl peptidase 4	-	Homo sapiens
dipeptidyl peptidase 4	-	Rattus norvegicus
DPP-4	-	Mus musculus
DPP-4	-	Homo sapiens
DPP-4	-	Rattus norvegicus

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Release 2023.1 (January 2023)