Application | Comment | Organism |
---|---|---|
medicine | DPP-4 inhibition is an oral therapy for type 2 diabetes | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alogliptin | competitive and reversible inhibitor | Homo sapiens | |
NVP DPP728 | - |
Homo sapiens | |
saxagliptin | BMS-477118, competitive and reversible inhibitor | Homo sapiens | |
sitagliptin | MK-0431 or Januvia, competitive and reversible inhibitor | Homo sapiens | |
vildagliptin | LAF237 or Galvus, competitive and reversible inhibitor | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | Homo sapiens | - |
? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | - |
Homo sapiens | ? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase-4 | - |
Homo sapiens |
DPP-4 | - |
Homo sapiens |