Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alogliptin | i.e. 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile monobenzoate, formerly SYR-322, potent and highly selective dipeptidyl peptidase-4 inhibitor, after 2 days alogliptin (0.002%, 0.01%, or 0.03%) dose-dependently inhibits DPP-4 activity by 28-82% | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | Mus musculus | - |
? | - |
? | |
glucosedependent insulinotropic polypeptide + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | - |
Mus musculus | ? | - |
? | |
glucosedependent insulinotropic polypeptide + H2O | - |
Mus musculus | ? | - |
? | |
Gly-L-Pro-4-nitroanilide | - |
Mus musculus | Gly-L-Pro + 4-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase-4 | - |
Mus musculus |
DPP-4 | - |
Mus musculus |