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Literature summary for 3.4.14.5 extracted from

  • Green, B.D.; Flatt, P.R.; Bailey, C.J.
    Inhibition of dipeptidylpeptidase IV activity as a therapy of type 2 diabetes (2006), Expert. Opin. Emerg. Drugs, 11, 525-539.
    View publication on PubMed
Search for more literature for 3.4.14.5

Application

Application Comment Organism
medicine inhibition of dipeptidylpeptidase IV activity as a therapy of type 2 diabetes Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucagon-like peptide-1 + H2O Homo sapiens dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect ?
-
 ?
glucose-dependent insulinotropic polypeptide + H2O Homo sapiens dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Homo sapiens
-
biliary duct
-
 Homo sapiens
-
brain endothelium Homo sapiens
-
endothelium of spleen, lung, brain and vessels supplying the liver Homo sapiens
-
gastrointestinal tract
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
lung endothelium Homo sapiens
-
lymph node
-
 Homo sapiens
-
mammary gland
-
 Homo sapiens
-
pancreas
-
 Homo sapiens
-
placenta
-
 Homo sapiens
-
prostate
-
 Homo sapiens
-
salivary gland
-
 Homo sapiens
-
spleen endothelium Homo sapiens
-
sweat gland
-
 Homo sapiens
-
thymus
-
 Homo sapiens
-
uterus
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha1-microglobulin + H2O
-
 Homo sapiens ?
-
 ?
aprotinin + H2O
-
 Homo sapiens ?
-
 ?
beta-casomorphin + H2O
-
 Homo sapiens ?
-
 ?
corticotropin-like intermediate lobe peptide + H2O
-
 Homo sapiens ?
-
 ?
enterostatin + H2O
-
 Rattus norvegicus ?
-
 ?
gastrin-releasing peptide + H2O
-
 Homo sapiens ?
-
 ?
glucagon-like peptide-1 + H2O dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect Homo sapiens ?
-
 ?
glucagon-like peptide-1 + H2O
-
 Homo sapiens ?
-
 ?
glucagon-like peptide-2 + H2O
-
 Mus musculus ?
-
 ?
glucose-dependent insulinotropic polypeptide + H2O dipeptidyl peptidase IV inactivates the hormone, thereby cancelling the prandial insulinotropic effect Homo sapiens ?
-
 ?
glucose-dependent insulinotropic polypeptide + H2O
-
 Homo sapiens ?
-
 ?
growth hormone-releasing hormone + H2O
-
 Homo sapiens ?
-
 ?
procolipase + H2O
-
 Homo sapiens ?
-
 ?
prolactin + H2O
-
 Homo sapiens ?
-
 ?
Substance P + H2O
-
 Homo sapiens ?
-
 ?
trypsinogen propeptide + H2O
-
 Homo sapiens ?
-
 ?
Tyr-melanostatin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
dipeptidylpeptidase IV
-
 Homo sapiens
dipeptidylpeptidase IV
-
 Mus musculus
dipeptidylpeptidase IV
-
 Rattus norvegicus
DPP IV
-
 Homo sapiens
DPP IV
-
 Mus musculus
DPP IV
-
 Rattus norvegicus