Inhibitors | Comment | Organism | Structure |
---|---|---|---|
sitagliptin | the systemic clearance of sitagliptin is driven primarily by renal elimination of intact parent drug | Canis lupus familiaris | |
sitagliptin | primary route of excretion of is via the kidneys, with a mean value of 87% of the administered dose recovered in urin. Because sitagliptin is eliminated primarily unchanged into urine, it is not expected to be a victim of metabolismbased drug interactions | Homo sapiens | |
sitagliptin | the systemic clearance of sitagliptin in rats is driven primarily by renal elimination of intact parent drug, with contribution from biliary excretion and metabolism (minor). Active transport mechanisms are probably involved in the renal elimination of sitagliptin | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase 4 | - |
Homo sapiens |