Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diisopropylfluorophosphate | marked inhibition at 1 mM | Streptococcus salivarius | |
Gly-Pro | competitive inhibition | Streptococcus salivarius | |
additional information | no inhibition by sulfhydryl-blocking agents and metal chelators, no inhibition by Pro, Pro-Gly, and Pro-Gly-Gly | Streptococcus salivarius |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | not affected by various cations | Streptococcus salivarius |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
47000 | - |
2 * 47000, SDS-PAGE | Streptococcus salivarius |
109000 | - |
gel filtration | Streptococcus salivarius |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus salivarius | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | the desialylated enzyme is attacked by proteases | Streptococcus salivarius |
Purification (Comment) | Organism |
---|---|
114fold | Streptococcus salivarius |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
release of an N-terminal dipeptide, Xaa-Yaa-/-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline | specific for hydrolysis of peptide bond on the carboxylic side of proline residues which are penultimate from the amino terminus | Streptococcus salivarius |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gly-Pro-4-nitroanilide + H2O | - |
Streptococcus salivarius | Gly-Pro + 4-nitroaniline | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 47000, SDS-PAGE | Streptococcus salivarius |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase IV | - |
Streptococcus salivarius |
DPPIV | - |
Streptococcus salivarius |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.7 | - |
Gly-NaOH buffer | Streptococcus salivarius |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
5.3 | - |
Gly-Pro | versus Gly-Pro-4-nitroanilide | Streptococcus salivarius |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Streptococcus salivarius | - |
- |
4.2 |