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Literature summary for 3.4.14.5 extracted from

  • David, F.; Bernard, A.M.; Pierres, M.; Marguet, D.
    Identification of serine 624, aspartic acid 702, and histidine 734 as the catalytic triad residues of mouse dipeptidyl-peptidase IV (CD26). A member of a novel family of nonclassical serine hydrolases (1993), J. Biol. Chem., 268, 17247-17252.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
D702A no hydrolyis of Gly-Pro-4-nitroanilide Mus musculus
D702E no hydrolyis of Gly-Pro-4-nitroanilide Mus musculus
H734L no hydrolyis of Gly-Pro-4-nitroanilide Mus musculus
H734R no hydrolyis of Gly-Pro-4-nitroanilide Mus musculus
S624A no hydrolyis of Gly-Pro-4-nitroanilide Mus musculus
S624T no hydrolysis of Gly-Pro-4-nitroanilide Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly-Pro-4-nitroanilide + H2O
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Mus musculus Gly-Pro + 4-nitroaniline
-
?
additional information Ser624, Asp702, and His734 form the catalytic triad Mus musculus ?
-
?