Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.14.4 extracted from

  • Wattiaux, R.; Wattiaux-de Coninck, S.; Thirion, J.; Gasingirwa, M.C.; Jadot, M.
    Lysosomes and Fas-mediated liver cell death (2007), Biochem. J., 403, 89-95.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.14.4

Activating Compound

Activating Compound Comment Organism Structure
aFas anti-fas antibody, aFas treated cells release lysosomal hydrolases into the culture medium Homo sapiens

Application

Application Comment Organism
medicine knowing whether lysosomal enzymes are involved in vivo in the Fas apoptotic pathway may be of some help to explore specific therapeutic targets for cell death inhibition in several severe liver pathologies Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
lysosome
-
 Homo sapiens 5764
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Arg-Arg-naphthylamide + H2O substrate used in the activity assay Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
dipeptidyl-peptidase III
-
 Homo sapiens
DPPIII
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 activity assay Homo sapiens