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Literature summary for 3.4.14.2 extracted from

  • Sakai, T.; Kojima, K.
    Rapid chromatographic purification of dipeptidyl-aminopeptidase II from human kidney (1987), J. Chromatogr., 416, 131-137.
    View publication on PubMed
Search for more literature for 3.4.14.2

Inhibitors

Inhibitors Comment Organism Structure
bestatin
-
 Homo sapiens
diisopropyl fluorophosphate
-
 Homo sapiens
phenylmethylsulfonyl fluoride
-
 Homo sapiens
Tris
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0457
-
 Ala-Pro-4-nitroanilide
-
 Homo sapiens
0.0457
-
 Lys-Pro-4-nitroanilide
-
 Homo sapiens
0.086
-
 Arg-Pro-4-nitroanilide
-
 Homo sapiens
0.282
-
 Gly-Pro-4-nitroanilide
-
 Homo sapiens
0.311
-
 Glu-Pro-4-nitroanilide
-
 Homo sapiens
0.93
-
 L-Lys-L-Ala-7-amido-4-methylcoumarin
-
 Homo sapiens
1.16
-
 Asp-Pro-4-nitroanilide
-
 Homo sapiens
1.22
-
 Ala-Ala-4-nitroanilide
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 2 * 55000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Ala-4-nitroanilide + H2O
-
 Homo sapiens Ala-Ala + 4-nitroaniline
-
 ?
Ala-Pro-4-nitroanilide + H2O
-
 Homo sapiens Ala-Pro + 4-nitroaniline
-
 ?
Arg-Pro-4-nitroanilide + H2O
-
 Homo sapiens Arg-Pro + 4-nitroaniline
-
 ?
Asp-Pro-4-nitroanilide + H2O
-
 Homo sapiens Asp-Pro + 4-nitroaniline
-
 ?
Glu-Pro-4-nitroanilide + H2O
-
 Homo sapiens Glu-Pro + 4-nitroaniline
-
 ?
Gly-Pro-4-nitroanilide + H2O
-
 Homo sapiens Gly-Pro + 4-nitroaniline
-
 ?
L-Lys-L-Ala-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens L-Lys-L-Ala + 7-amino-4-methylcoumarin
-
 ?
Lys-Ala-4-methylcoumaryl-7-amide + H2O
-
 Homo sapiens Lys-Ala + 7-amino-4-methylcoumarin
-
 ?
Lys-Pro-4-nitroanilide + H2O
-
 Homo sapiens Lys-Pro + 4-nitroaniline
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 55000, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.3
-
 hydrolysis of Lys-Ala-4-methylcoumarinamide Homo sapiens