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Literature summary for 3.4.14.2 extracted from

  • Mantle, D.
    Characterization of dipeptidyl and tripeptidyl aminopeptidases in human kidney soluble fraction (1991), Clin. Chim. Acta, 196, 135-142.
    View publication on PubMed

Application

Application Comment Organism
analysis the enzyme is a potential urinary marker for the biochemical detection of kidney damage Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Cd2+
-
Homo sapiens
Co2+
-
Homo sapiens
Cu2+
-
Homo sapiens
Hg2+
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Lys-Ala-4-methylcoumaryl-7-amide + H2O
-
Homo sapiens Lys-Ala + 7-amino-4-methylcoumarin
-
?
Phe-Pro-4-methylcoumarin 7-amide + H2O
-
Homo sapiens Phe-Pro + 7-amino-4-methylcoumarin
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
-
Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
4 7 50% of maximal activity at pH 4 and 7 Homo sapiens