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Literature summary for 3.4.14.1 extracted from

  • McDonald, J.K.; Callahan, P.X.; Ellis, S.
    Preparation and specificity of dipeptidyl aminopeptidase I (1972), Methods Enzymol., 25B, 272-281.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
hypophysis
-
Bos taurus
-
liver
-
Rattus norvegicus
-
spleen
-
Rattus norvegicus
-
spleen
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
18.6
-
-
Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Ala-2-naphthylamide + H2O
-
Bos taurus Ala-Ala + 2-naphthylamine
-
?
Ala-Arg-2-naphthylamide + H2O
-
Bos taurus Ala-Arg + 2-naphthylamine
-
?
beta-corticotropin + H2O succesive removal of dipeptides from the NH2 terminus Rattus norvegicus Ser-Tyr + Ser-Met + Glu-His + Phe-Arg + Trp-Gly
-
?
beta-corticotropin + H2O succesive removal of dipeptides from the NH2 terminus Bos taurus Ser-Tyr + Ser-Met + Glu-His + Phe-Arg + Trp-Gly
-
?
Glu-His-2-naphthylamide + H2O
-
Bos taurus Glu-His + 2-naphthylamine
-
?
Gly-Arg-2-naphthylamide + H2O
-
Rattus norvegicus Gly-Arg + 2-naphthylamine
-
?
Gly-Phe-2-naphthylamide + H2O
-
Bos taurus Gly-Phe + 2-naphthylamine
-
?
Gly-Trp-2-naphthylamide + H2O
-
Bos taurus Gly-Trp + 2-naphthylamine
-
?
additional information inability to remove dipeptides with an N-terminal Arg or Lys, and inability to cleave the bond on either side of Pro Rattus norvegicus ?
-
?
additional information inability to remove dipeptides with an N-terminal Arg or Lys, and inability to cleave the bond on either side of Pro Bos taurus ?
-
?
Phe-Arg-2-naphthylamide + H2O
-
Bos taurus Phe-Arg + 2-naphthylamine
-
?
Pro-Arg-2-naphthylamide + H2O
-
Bos taurus Pro-Arg + 2-naphthylamine
-
?
Ser-Met-2-naphthylamide + H2O
-
Bos taurus Ser-Met + 2-naphthylamine
-
?
Ser-Tyr-2-naphthylamide + H2O
-
Bos taurus Ser-Tyr + 2-naphthylamine
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
-
Bos taurus