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Literature summary for 3.4.13.20 extracted from

  • Bellia, F.; Calabrese, V.; Guarino, F.; Cavallaro, M.; Cornelius, C.; De Pinto, V.; Rizzarelli, E.
    Carnosinase levels in aging brain: redox state induction and cellular stress response (2009), Antioxid. Redox Signal., 11, 2759-2775.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
a stable HeLa cell line expressing recombinant human serum carnosinase CN1 is established Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
using DEAE Sephacel and UnoQ chromatography Homo sapiens

Synonyms

Synonyms Comment Organism
CN1
-
Homo sapiens

General Information

General Information Comment Organism
malfunction HeLa-CN1 cells have a lower cell survival than do non-transfected cells or HeLa cells transfected with an empty or a mock vector. Viability in HeLa cells measured after H2O2 treatment is significantly higher than the viability of HeLa-CN1 cells after the same oxidant insult, indicating an increased susceptibility to oxidative stress of cells overexpressing carnosinase Homo sapiens