Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Ba2+ | - |
Gloydius brevicaudus | |
BaCl2 | 319% residual activity at a concentration of 1 mM | Gloydius brevicaudus | |
Ca2+ | - |
Gloydius brevicaudus | |
CaCl2 | 473% residual activity at a concentration of 1 mM | Gloydius brevicaudus | |
Mn2+ | - |
Gloydius brevicaudus | |
MnCl2 | 181% residual activity at a concentration of 1 mM | Gloydius brevicaudus |
Cloned (Comment) | Organism |
---|---|
- |
Gloydius brevicaudus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | 0% residual activity at a concentration of 1 mM | Gloydius brevicaudus | |
amastin | 3% residual activity at a concentration of 0.001 mM | Gloydius brevicaudus | |
bestatin | 38% residual activity at a concentration of 0.03 mM | Gloydius brevicaudus | |
EDTA | 7% residual activity at a concentration of 5 mM | Gloydius brevicaudus | |
Zn2+ | - |
Gloydius brevicaudus | |
ZnCl2 | 0% residual activity at a concentration of 1 mM | Gloydius brevicaudus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bothrops jararaca | - |
- |
- |
Crotalus atrox | - |
- |
- |
Gloydius blomhoffii | - |
- |
- |
Gloydius brevicaudus | - |
- |
- |
Protobothrops flavoviridis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Gloydius blomhoffi brevicaudus venom is centrifuged and the resulting supernatant is subjected to gel-filtration on a Sephacryl S-300 column | Gloydius brevicaudus |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000003 | - |
substrate Glu-4-methyl-coumaryl-7-amide | Crotalus atrox |
0.0000071 | - |
substrate Glu-4-methyl-coumaryl-7-amide | Protobothrops flavoviridis |
0.0000071 | - |
substrate Glu-4-methyl-coumaryl-7-amide | Gloydius blomhoffii |
0.0000138 | - |
substrate Glu-4-methyl-coumaryl-7-amide | Bothrops jararaca |
0.000014 | - |
substrate Glu-4-methyl-coumaryl-7-amide | Gloydius brevicaudus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Glu-4-methylcoumaryl-7-amide + H2O | - |
Crotalus atrox | Glu + 7-amino-4-methylcoumarin | - |
? | |
Glu-7-amido-4-methylcoumarin + H2O | - |
Gloydius brevicaudus | Glu + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aminopeptidase A | - |
Protobothrops flavoviridis |
aminopeptidase A | - |
Crotalus atrox |
aminopeptidase A | - |
Bothrops jararaca |
aminopeptidase A | - |
Gloydius blomhoffii |
aminopeptidase A | - |
Gloydius brevicaudus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
activity assay | Protobothrops flavoviridis |
37 | - |
activity assay | Crotalus atrox |
37 | - |
activity assay | Bothrops jararaca |
37 | - |
activity assay | Gloydius blomhoffii |
37 | - |
activity assay | Gloydius brevicaudus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
activity assay | Protobothrops flavoviridis |
7.4 | - |
activity assay | Crotalus atrox |
7.4 | - |
activity assay | Bothrops jararaca |
7.4 | - |
activity assay | Gloydius blomhoffii |
7.4 | - |
activity assay | Gloydius brevicaudus |