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Literature summary for 3.4.11.6 extracted from

  • Millership, J.J.; Chappell, C.; Okhuysen, P.C.; Snowden, K.F.
    Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae (2002), J. Parasitol., 88, 843-848.
    View publication on PubMed
Search for more literature for 3.4.11.6

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 68.5% inhibition at 5 mM Vittaforma corneae
bestatin 84.8% inhibition at 0.3 mM Vittaforma corneae
additional information no inhibition by epibestatin, and by E64, chymostatin, leupeptin, and antipain Vittaforma corneae
nitrobestatin 92.3% inhibition at 0.133 mM Vittaforma corneae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Vittaforma corneae 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
78000
-
 native PAGE Vittaforma corneae

Organism

Organism UniProt Comment Textmining
Vittaforma corneae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partially, preparation of spores and subcellular fractionation Vittaforma corneae

Source Tissue

Source Tissue Comment Organism Textmining
spore
-
 Vittaforma corneae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala-7-amido-4-methylcoumarin + H2O
-
 Vittaforma corneae L-Ala + 7-amino-4-methylcoumarin
-
 ?
L-Arg-7-amido-4-methylcoumarin + H2O best substrate Vittaforma corneae L-Arg + 7-amino-4-methylcoumarin
-
 ?
L-Leu-7-amido-4-methylcoumarin + H2O
-
 Vittaforma corneae L-Leu + 7-amino-4-methylcoumarin
-
 ?
L-Met-7-amido-4-methylcoumarin + H2O no activity with Z-Met-7-amido-4-methylcoumarin Vittaforma corneae L-Met + 7-amino-4-methylcoumarin
-
 ?
L-Phe-7-amido-4-methylcoumarin + H2O low activity Vittaforma corneae L-Phe + 7-amino-4-methylcoumarin
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Vittaforma corneae