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Literature summary for 3.4.11.4 extracted from

  • Chikuma, T.; Shimizu, M.; Tsuchiya, Y.; Kato, T.; Hojo, H.
    Axonal transports of tripeptidyl peptidase II in rat sciatic nerves (2007), Neurochem. Int., 50, 236-242.
    View publication on PubMed
Search for more literature for 3.4.11.4

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline strongly inhibitory at 1 mM Rattus norvegicus
Ala-Ala-Phe-chloromethyl ketone 85-90% inhibition at 1 mM Rattus norvegicus
Ca2+ partial inhibition at 1 mM Rattus norvegicus
Cu2+ strongly inhibitory at 1 mM Rattus norvegicus
diisopropylfluorophosphate strongly inhibitory at 1 mM Rattus norvegicus
EDTA partial inhibition at 1 mM Rattus norvegicus
Fe2+ partial inhibition at 1 mM Rattus norvegicus
Hg2+ strongly inhibitory at 0.1 mM Rattus norvegicus
iodoacetic acid partial inhibition at 1 mM Rattus norvegicus
Mg2+ partial inhibition at 1 mM Rattus norvegicus
Mn2+ partial inhibition at 1 mM Rattus norvegicus
N-ethylmaleimide partial inhibition at 1 mM Rattus norvegicus
p-chloromercuriphenylsulfonic acid strongly inhibitory at 1 mM Rattus norvegicus
Zn2+ partial inhibition at 1 mM Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sciatic nerve
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O
-
 Rattus norvegicus Ala-Ala-Phe + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
EC 3.4.14.10 formerly Rattus norvegicus
TPPII
-
 Rattus norvegicus
tripeptidyl peptidase II
-
 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
6 7.8
-
 Rattus norvegicus