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Literature summary for 3.4.11.21 extracted from

  • Iribar, C.; Esteban, M.J.; Martinez, J.M.; Peinado, J.M.
    Decrease in cytosolic aspartyl-aminopeptidase but not in alanyl-aminopeptidase activity in the frontal cortex of the aged rat (1995), Brain Res., 687, 211-213.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Rattus sp. 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensin + H2O Rattus sp.
-
Asp + des-Asp-angiotensin
-
?
aspartyl peptides + H2O Rattus sp. activation and degradation of several neuropeptides, excitatory Asp and Glu implicated in pathogenesis of different neurogeneratives diseases Asp + des-Asp-angiotensin
-
?

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus sp.
-
frontal lobe 29 and 33 months old rats show a 50% decrease of enzymatic activity Rattus sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin + H2O
-
Rattus sp. Asp + des-Asp-angiotensin
-
?
Asp 2-naphthylamide + H2O
-
Rattus sp. Asp + 2-naphthylamine
-
?
aspartyl peptides + H2O activation and degradation of several neuropeptides, excitatory Asp and Glu implicated in pathogenesis of different neurogeneratives diseases Rattus sp. Asp + des-Asp-angiotensin
-
?

Synonyms

Synonyms Comment Organism
Asp-AP
-
Rattus sp.
aspartyl-AP
-
Rattus sp.
EC 3.4.11.7 related Rattus sp.