Literature summary for 3.4.11.2 extracted from

Kuehlmann, U.C.; Chwieralski, C.E.; van den Brule, S.; Roecken, C.; Reinhold, D.; Welte, T.; Buehling, F.
Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases (2009), Life Sci., 84, 1-11.

Search for more literature for 3.4.11.2

Inhibitors

Inhibitors	Comment	Organism	Structure
actinonin	actinonin, an inhibitor of aminopeptidase N, may modulate chemokine secretion in the lung and thus attenuate the development of lung fibrosis	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	dependent on	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
A-549 cell	-	Homo sapiens	-
lung epithelial cell	-	Homo sapiens	-
monocyte	alveolar monocyte	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-Ala-p-nitroanilide + H2O	-	Homo sapiens	L-Ala + p-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
aminopeptidase N	-	Homo sapiens
APN	-	Homo sapiens
CD13	-	Homo sapiens

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Release 2023.1 (January 2023)