Literature summary for 3.4.11.2 extracted from

Rangel, R.; Sun, Y.; Guzman-Rojas, L.; Ozawa, M.G.; Sun, J.; Giordano, R.J.; Van Pelt, C.S.; Tinkey, P.T.; Behringer, R.R.; Sidman, R.L.; Arap, W.; Pasqualini, R.
Impaired angiogenesis in aminopeptidase N-null mice (2007), Proc. Natl. Acad. Sci. USA, 104, 4588-4593.

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Application

Application	Comment	Organism
medicine	aminopeptidase N-null mice develop normally without physiological alterations and can undergo physiological angiogenesis but show a severely impaired angiogenic response under pathological conditions	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	mice with targeted disruption of the aminopeptidase N gene develop with no gross or histological abnormalities. In oxygen-induced retinopathy experiments, enzyme deficient mice have a marked and dose-dependent deficiency of the expected retinal neovascularization	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

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Release 2023.1 (January 2023)