Literature summary for 3.4.11.2 extracted from

de Gortari, P.; Vargas, M.A.; Martinez, A.; Garcia-Vazquez, A.I.; Uribe, R.M.; Chavez-Gutierrez, L.; Magdaleno, V.; Boileau, G.; Charli, J.L.; Joseph-Bravo, P.
Stage-specific modulation of neprilysin and aminopeptidase N in the limbic system during kindling progression (2007), J. Mol. Neurosci., 33, 252-261.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	of fully or partially kindled rats. Aminopeptidase N mRNA levels are decreased at stage II and increased at stage V of kindling, in frontal cortex-olfactory tubercle, and hippocampus. Neprilysin and aminopeptidase N enzymatic activities, follow similar variations to their respective mRNA levels. The coordinated changes of neprilysin and aminopeptidase N expression are opposite to those previously observed for pyroglutamyl peptidaseII mRNA and activity levels in limbic regions	Rattus norvegicus	-

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Release 2023.1 (January 2023)