Literature summary for 3.4.11.2 extracted from

Mina-Osorio, P.; Shapiro, L.H.; Ortega, E.
CD13 in cell adhesion: aminopeptidase N (CD13) mediates homotypic aggregation of monocytic cells (2006), J. Leukoc. Biol., 79, 719-730.

Search for more literature for 3.4.11.2

Application

Application	Comment	Organism
medicine	anti-CD13 monoclonal antibodies induce homotypic aggregation of monocytic U-937 cells, independently of their effect on enzymatic activity. The induction is related to binding to a specific site on the Cd13 molecule and independent of integrins. During homotypic aggregation, CD13 actively redistributes to the zones of cell-cell contact	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
U-937 cell	-	Homo sapiens	-

Subunits

Subunits	Comment	Organism
More	anti-CD13 monoclonal antibodies induce homotypic aggregation of monocytic U-937 cells, independently of their effect on enzymatic activity. The induction is related to binding to a specific site on the Cd13 molecule and independent of integrins. During homotypic aggregation, CD13 actively redistributes to the zones of cell-cell contact	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)