Application | Comment | Organism |
---|---|---|
medicine | simultaneous application of inhibitors to dipeptidyl peptidase IV and aminopeptidase N leads to a more profound reduction of the clinical severity of the experimental autoimmune encephalomyelitis compared to the use of dipeptidyl peptidase IV or aminopeptidase N inhibitors alone | Mus musculus |
medicine | simultaneous application of inhibitors to dipeptidyl peptidase IV and aminopeptidase N significantly suppresses DNA synthesis and markedly increases TGF-beta1 production in mitogen- or anti-CD3-stimulated T cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
actinonin | - |
Homo sapiens | |
actinonin | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
animals with experimental autoimmune encephalomyelitis | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
T-cell | mitogen- or anti-CD3-stimulated T-cell. Simultaneous application of inhibitors to dipeptidyl peptidase IV and aminopeptidase N significantly suppresses DNA synthesis and markedly increases TGF-beta1 production | Homo sapiens | - |