Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amastatin | strong inhibition | Cavia porcellus | |
bestatin | strong inhibition | Cavia porcellus | |
metal chelators | strong inhibition | Cavia porcellus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.6 | - |
L-Ala-4-nitroanilide | - |
Cavia porcellus | |
18 | - |
L-Ala-D-iso-Gln-meso-DAP(omegaNH2)-D-Ala-D-Ala | - |
Cavia porcellus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Cavia porcellus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
175000 | - |
gel filtration | Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native L,(L/D)-aminopeptidase 700fold from serum to homogeneity in 4 chromatographic steps | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
enkephalin + H2O | enkephalins comprising L,L- and L,D-peptide bonds | Cavia porcellus | ? | - |
? | |
L-Ala-4-nitroanilide + H2O | - |
Cavia porcellus | L-Ala + 4-nitroaniline | - |
? | |
L-Ala-D-iso-Gln-meso-DAP(omegaNH2)-D-Ala-D-Ala + H2O | - |
Cavia porcellus | L-Ala + D-iso-Gln-meso-DAP(omegaNH2)-D-Ala-D-Ala | product identification and stereochemic determination | ? | |
additional information | the enzyme hydrolyzes several peptides with N-terminal L-amino acids, but not with N-terminal D-amino acids, no activity with L-Asp-L-Asp | Cavia porcellus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L,(L/D)-aminopeptidase | - |
Cavia porcellus |