Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme is puromycin-insensitive | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Rattus norvegicus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Wistar rats | - |
Purification (Comment) | Organism |
---|---|
partially, subcellular fractionation | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Rattus norvegicus | - |
heart | - |
Rattus norvegicus | - |
kidney | cortex and medulla | Rattus norvegicus | - |
lung | - |
Rattus norvegicus | - |
additional information | enzyme in visceral organs during alterations in body fluid volume and osmolality, overview | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
enzyme activities in membrane fractions of heat, kidney, lung, and adrenal gland from PEG-treated rats, acute salt-loaded rats, water-overloaded rats, salt-loaded rats, and water-deprived rats, overview | Rattus norvegicus |
0.0035 | - |
normal healthy rats, membrane fraction of heart, APN-PI | Rattus norvegicus |
0.0086 | - |
normal healthy rats, membrane fraction of adrenal gland, APN-PI | Rattus norvegicus |
0.0115 | - |
normal healthy rats, membrane fraction of kidney medulla, APN-PI | Rattus norvegicus |
0.0238 | - |
normal healthy rats, membrane fraction of lung, APN-PI | Rattus norvegicus |
0.0891 | - |
normal healthy rats, membrane fraction of kidney cortex, APN-PI | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ala-2-naphthylamide + H2O | - |
Rattus norvegicus | L-Ala + 2-naphthylamine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
APN | - |
Rattus norvegicus |
APN-PI | - |
Rattus norvegicus |
puromycin-insensitive neutral aminopeptidase | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |