Cloned (Comment) | Organism |
---|---|
transient expression of wild-type and mutant enzymes in murine BALB/3T3 fibroblasts, and stable expression in CL1-0 cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
Homo sapiens | 9986 | - |
plasma membrane | - |
Homo sapiens | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme can associate with tumor-associated antigen L6, TAL6, and enhance the motility of human lung cancer cells and their adhesion to extracellular matrix, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
CL1-5 cell | highly invasive lung adenocarcinoma cell line, high expression level | Homo sapiens | - |
HT-1080 cell | fibrosarcoma cell line | Homo sapiens | - |
HUT-125 cell | lung adenocarcinoma cell line | Homo sapiens | - |
lung | - |
Homo sapiens | - |
lung adenocarcinoma cell | - |
Homo sapiens | - |
additional information | no or poor expression in poorly invasive lung adenocarcinoma CL1-0 cells | Homo sapiens | - |
PC-3 cell | prostate adenocarcinoma cell line | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ala-4-nitroanilide + H2O | - |
Homo sapiens | L-Ala + 4-nitroaniline | - |
? | |
additional information | the enzyme can associate with tumor-associated antigen L6, TAL6, and enhance the motility of human lung cancer cells and their adhesion to extracellular matrix, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aminopeptidase N | - |
Homo sapiens |
CD13 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
in vivo assay at | Homo sapiens |