Any feedback?
Literature summary for 3.4.11.2 extracted from
- Intestinal surface peptide hydrolases: identification and characterization of three enzymes from rat brush border (1975), Biochim. Biophys. Acta, 403, 147-160.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | - |
Rattus norvegicus |  |
| EDTA | 100% inhibition at 5 mM | Rattus norvegicus | |
| Mg2+ | - |
Rattus norvegicus | |
| Mn2+ | - |
Rattus norvegicus | |
| Zn2+ | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.06 | 0.076 | Leu-Gly | - |
Rattus norvegicus | |
| 0.41 | 0.79 | Leu-2-naphthylamide | - |
Rattus norvegicus | |
| 0.6 | 0.76 | Leu-Gly | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | brush border membrane | Rattus norvegicus | 16020 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 160000 | - |
peptidase II, density gradient centrifugation | Rattus norvegicus |
| 230000 | - |
peptidase I, density gradient centrifugation | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| aminoacyl peptide | Rattus norvegicus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 2 isoenzymes | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| aminoacyl peptide | - |
Rattus norvegicus | ? | - |
? | |
| aminoacyl peptide + H2O | - |
Rattus norvegicus | alanyl peptides + H2O | - |
? | |
| dipeptides + H2O | - |
Rattus norvegicus | amino acids | - |
? | |
| Leu-2-naphthylamide + H2O | - |
Rattus norvegicus | Leu + 2-naphthylamine | - |
? | |
| Leu-Gly + H2O | - |
Rattus norvegicus | Leu + Gly | - |
? | |
| tripeptides + H2O | - |
Rattus norvegicus | dipeptides + amino acids | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
