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Literature summary for 3.4.11.16 extracted from
- Inhibitor profile of porcine aminopeptidase W (1993), Biochem. Soc. Trans., 21, 250S.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | chemotherapeutic target, involved in heart disease, metastasis, inflammation | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| amastatin | 50% inhibition at 0.00158 mM | Sus scrofa |  |
| bestatin | - |
Homo sapiens | |
| bestatin | 50% inhibition at 0.0079 mM | Sus scrofa | |
| additional information | overlap of inhibitory effects of typical aminopeptidase inhibitors with other enzymes | Sus scrofa | |
| probestin | 50% inhibition at 0.005 mM | Sus scrofa | |
| rentiapril | 50% inhibition at 0.0016 mM | Sus scrofa | |
| zofenoprilat | 50% inhibition at 0.018 mM | Sus scrofa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| peripheral nervous system | - |
Homo sapiens | - |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
| 37 | - |
assay at | Sus scrofa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Sus scrofa |
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Release 2023.1 (January 2023)
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