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Literature summary for 3.3.2.9 extracted from
- Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs (1993), J. Biol. Chem., 268, 19604-19609.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,1,1-trifluoro-2-propanone | - |
Manduca sexta |  |
| 5,5'-dithiobis(2-nitrobenzoic acid) | - |
Manduca sexta | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00028 | - |
juvenile hormone III | - |
Manduca sexta | |
| 0.00055 | - |
juvenile hormone II | - |
Manduca sexta | |
| 0.00061 | - |
juvenile hormone I | - |
Manduca sexta | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Manduca sexta | 5829 | - |
| membrane | - |
Manduca sexta | 16020 | - |
| microsome | - |
Manduca sexta | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | - |
x * 50000, SDS-PAGE | Manduca sexta |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Manduca sexta | the enzyme may play a significant role in the secondary metabolism of juvenile hormone acid generated by juvenile hormone esterase | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Manduca sexta | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Manduca sexta |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| egg | - |
Manduca sexta | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0083 | - |
- |
Manduca sexta |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| juvenile hormone I + H2O | - |
Manduca sexta | ? | - |
? | |
| juvenile hormone II + H2O | - |
Manduca sexta | ? | - |
? | |
| juvenile hormone III + H2O | - |
Manduca sexta | ? | - |
? | |
| additional information | the enzyme may play a significant role in the secondary metabolism of juvenile hormone acid generated by juvenile hormone esterase | Manduca sexta | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 50000, SDS-PAGE | Manduca sexta |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 90 | - |
1 min, complete loss of activity | Manduca sexta |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.08 | - |
juvenile hormone III | - |
Manduca sexta | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 8.5 | - |
Manduca sexta |
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Release 2023.1 (January 2023)
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