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Literature summary for 3.3.2.6 extracted from
- Development of predictive quantitative structure-activity relationship model and its application in the discovery of human leukotriene A4 hydrolase inhibitors (2013), Future Med. Chem., 5, 27-40.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | inhibition of this enzyme can be a valid method in the treatment of inflammatory response exhibited through leukotriene B4 | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene A4 + H2O | Homo sapiens | - |
leukotriene B4 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene A4 + H2O | - |
Homo sapiens | leukotriene B4 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| leukotriene A4 hydrolase | - |
Homo sapiens |
| LTA4H | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme plays a key role in innate immune responses | Homo sapiens |
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