Cloned (Comment) | Organism |
---|---|
semiquantitative LTA4H expression analysis in peripheral nerves and spinal cord, overview | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
leukotriene A4 + H2O | Rattus norvegicus | - |
leukotriene B4 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P30349 | male Sprague Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
microglia | - |
Rattus norvegicus | - |
nerve | peripheral | Rattus norvegicus | - |
neuron | - |
Rattus norvegicus | - |
spinal cord | enzyme expression analysis, LTA4h mRNA is expressed in both spinal neurons and microglia, overview | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
leukotriene A4 + H2O | - |
Rattus norvegicus | leukotriene B4 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LTA4 hydrolase | - |
Rattus norvegicus |
LTA4H | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
malfunction | increase of leukotriene synthesis in spinal microglia produced via p38 MAPK plays a role in the generation of neuropathic pain | Rattus norvegicus |