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Literature summary for 3.3.2.6 extracted from

  • Nathaniel, D.J.; Evans, J.F.; Leblanc, Y.; Leveille, C.; Fitzsimmons, B.J.; Ford-Hutchinson, A.W.
    Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase (1985), Biochem. Biophys. Res. Commun., 131, 827-835.
    View publication on PubMed
Search for more literature for 3.3.2.6

Application

Application Comment Organism
medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Homo sapiens
medicine the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Leukotriene A5
-
 Homo sapiens
Leukotriene A5
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
leukotriene A4 + H2O Homo sapiens biosynthesis of leukotriene B4 leukotriene B4
-
 ?
leukotriene A4 + H2O Rattus norvegicus biosynthesis of leukotriene B4 leukotriene B4
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
-
 Homo sapiens
-
neutrophil
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
leukotriene A4 + H2O
-
 Homo sapiens leukotriene B4
-
 ?
leukotriene A4 + H2O
-
 Rattus norvegicus leukotriene B4
-
 ?
leukotriene A4 + H2O biosynthesis of leukotriene B4 Homo sapiens leukotriene B4
-
 ?
leukotriene A4 + H2O biosynthesis of leukotriene B4 Rattus norvegicus leukotriene B4
-
 ?
leukotriene A5 + H2O i.e. 5(S)-trans-5,6-oxido-7,9-trans-11,14,17-cis-eicosatetraenoic acid Homo sapiens ?
-
 ?
leukotriene A5 + H2O i.e. 5(S)-trans-5,6-oxido-7,9-trans-11,14,17-cis-eicosatetraenoic acid Rattus norvegicus ?
-
 ?