Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Emulgen 108 | complete inactivation | Mus musculus | |
Emulgen 911 | complete inactivation | Mus musculus | |
Lubrol Px | complete inactivation | Mus musculus | |
sodium cholate | - |
Mus musculus | |
Triton WR-1339 | - |
Mus musculus | |
Tween 80 | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O | Mus musculus | the substrate is a product of lipid peroxidation in the liver | cholestane-3beta,5alpha,6beta-triol | - |
? | |
additional information | Mus musculus | the enzyme is distinct from the microsomal epoxide hydrolase EC 3.3.2.9, which shows a wider xenobiotic substrate specificity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partially from liver by micosome preparation, two steps of gel filtration, separation from the xenobiotic epoxide hydrolase, EC 3.3.2.9 | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00033 | - |
liver microsomes | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O | - |
Mus musculus | cholestane-3beta,5alpha,6beta-triol | - |
? | |
5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O | the substrate is a product of lipid peroxidation in the liver | Mus musculus | cholestane-3beta,5alpha,6beta-triol | - |
? | |
additional information | the enzyme is distinct from the microsomal epoxide hydrolase EC 3.3.2.9, which shows a wider xenobiotic substrate specificity | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CEHase | - |
Mus musculus |
cholesterol epoxide hydrolase | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Mus musculus |