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Literature summary for 3.3.2.10 extracted from

  • Luo, B.; Norris, C.; Bolstad, E.S.; Knecht, D.A.; Grant, D.F.
    Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolase (2008), J. Mol. Biol., 380, 31-41.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in CHO cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
R287Q the mutant enzyme is less stable than the wild type sEH Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol sEH shows both, peroxisomal and cytosolic localizations in vivo Homo sapiens 5829
-
peroxisome sEH shows both, peroxisomal and cytosolic localizations in vivo, peroxisomal import occurs when expression levels are high or when the Ser-Lys-Met motif (amino acids 553-555) is accessible Homo sapiens 5777
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P34913
-
-

Synonyms

Synonyms Comment Organism
SEH
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Homo sapiens