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Literature summary for 3.3.2.10 extracted from

  • Motoki, A.; Merkel, M.J.; Packwood, W.H.; Cao, Z.; Liu, L.; Iliff, J.; Alkayed, N.J.; Van Winkle, D.M.
    Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo (2008), Am. J. Physiol. Heart Circ. Physiol., 295, H2128-H2134.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.3.2.10

Application

Application Comment Organism
medicine soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo and reduce the infarct size Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl ester selective sEH inhibitor Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
myocardium
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(5Z,8Z,11Z)-14,15-epoxyeicosa-5,8,11-trienoic acid + H2O i.e. 14,15-EET Mus musculus (5Z,8Z,11Z)-14,15-dihydroxyeicosa-5,8,11-trienoic acid i.e. 14,15-DHET ?

Synonyms

Synonyms Comment Organism
SEH
-
 Mus musculus