Any feedback?
Literature summary for 3.3.2.10 extracted from
- Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism (2004), Toxicol. Sci., 78, 187-195.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | the enzyme is induced by clofibrate in liver not in epididymis | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | - |
x * 65000, SDS-PAGE | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 11,12-epoxyeicosatrienoic acid + H2O | Rattus norvegicus | - |
11,12-dihydroxyeicosatrienoic acid | - |
? |  |
| 14,15-epoxyeicosatrienoic acid + H2O | Rattus norvegicus | - |
14,15-dihydroxyeicosatrienoic acid | - |
? | |
| 5,6-epoxyeicosatrienoic acid + H2O | Rattus norvegicus | - |
5,6-dihydroxyeicosatrienoic acid | - |
? | |
| 8,9-epoxyeicosatrienoic acid + H2O | Rattus norvegicus | - |
8,9-dihydroxyeicosatrienoic acid | - |
? | |
| additional information | Rattus norvegicus | the enzyme is involved in the arachidonic acid metabolic pathway | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
male Sprague-Dawley | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epididymis | caput, corpus, cauda | Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| testis | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.00051 | - |
epididymis cytosol | Rattus norvegicus |
| 0.001 | - |
liver cytosol | Rattus norvegicus |
| 0.0027 | - |
kidney cytosol | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 11,12-epoxyeicosatrienoic acid + H2O | - |
Rattus norvegicus | 11,12-dihydroxyeicosatrienoic acid | - |
? | |
| 14,15-epoxyeicosatrienoic acid + H2O | - |
Rattus norvegicus | 14,15-dihydroxyeicosatrienoic acid | - |
? | |
| 5,6-epoxyeicosatrienoic acid + H2O | - |
Rattus norvegicus | 5,6-dihydroxyeicosatrienoic acid | - |
? | |
| 8,9-epoxyeicosatrienoic acid + H2O | - |
Rattus norvegicus | 8,9-dihydroxyeicosatrienoic acid | - |
? | |
| additional information | the enzyme is involved in the arachidonic acid metabolic pathway | Rattus norvegicus | ? | - |
? | |
| trans-diphenylpropene oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 65000, SDS-PAGE | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SEH | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
