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Literature summary for 3.3.2.10 extracted from

  • Schladt, L.; Hartman, R.; Woerner, W.; Thomas, H.; Oesch, F.
    Purification and characterization of rat-liver cytosolic epoxide hydrolase (1988), Eur. J. Biochem., 176, 31-37.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
acetone hydration of trans-stilbene oxide Rattus norvegicus
acetonitrile hydration of trans-stilbene oxide Rattus norvegicus
ethanol hydration of trans-stilbene oxide Rattus norvegicus
Isopropanol hydration of trans-stilbene oxide Rattus norvegicus
methanol hydration of trans-stilbene oxide Rattus norvegicus
N,N-Dimethyl formamide hydration of trans-stilbene oxide Rattus norvegicus
tetrahydrofuran hydration of trans-stilbene oxide Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0017
-
trans-stilbene oxide
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
2 * 60000, SDS-PAGE Rattus norvegicus
120000
-
gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.173
-
-
Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
styrene 7,8-oxide + H2O
-
Rattus norvegicus styrene glycol
-
?
trans-ethyl styrene oxide + H2O trans-beta-ethyl styrene oxide Rattus norvegicus ?
-
?
trans-stilbene oxide + H2O
-
Rattus norvegicus ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 60000, SDS-PAGE Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
6 9 pH 6.0: about 35% of maximal activity, pH 9.0: about 60% of maximal activity Rattus norvegicus