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Literature summary for 3.2.2.5 extracted from

  • Tang, J.Y.; Bullen, N.P.; Ahmad, S.; Whitney, J.C.
    Diverse NADase effector families mediate interbacterial antagonism via the type VI secretion system (2018), J. Biol. Chem., 293, 1504-1514 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.5

Cloned(Commentary)

Cloned (Comment) Organism
-
 Pseudomonas protegens

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with effector Tni2, to 1.7 A resolution Pseudomonas protegens

Protein Variants

Protein Variants Comment Organism
R343A about 100fold decrease in activity Pseudomonas protegens
R343A/K353A more than 1000fold decrease in activity Pseudomonas protegens

Organism

Organism UniProt Comment Textmining
Pseudomonas protegens Q4K3B6
-
-
Pseudomonas protegens ATCC BAA-477 Q4K3B6
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + H2O
-
 Pseudomonas protegens ADP-D-ribose + nicotinamide
-
 ?
NAD+ + H2O
-
 Pseudomonas protegens ATCC BAA-477 ADP-D-ribose + nicotinamide
-
 ?
NADP+ + H2O
-
 Pseudomonas protegens phospho-ADP-ribose + nicotinamide
-
 ?
NADP+ + H2O
-
 Pseudomonas protegens ATCC BAA-477 phospho-ADP-ribose + nicotinamide
-
 ?

Synonyms

Synonyms Comment Organism
PAAR motif containing protein
-
 Pseudomonas protegens
PFL_6209
-
 Pseudomonas protegens

Cofactor

Cofactor Comment Organism Structure
NAD+ NAD+ is 2fold preferred over NADP+ Pseudomonas protegens
NADP+ NAD+ is 2fold preferred over NADP+ Pseudomonas protegens